Which statement best reflects the LDL-C target for very high-risk ASCVD patients?

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Multiple Choice

Which statement best reflects the LDL-C target for very high-risk ASCVD patients?

In patients with established ASCVD who are at very high risk, the goal is marked LDL-C lowering to reduce the chance of another event. Reaching an LDL-C level below 70 mg/dL provides a substantial reduction in recurrent cardiovascular events and is the standard target for secondary prevention in this group. Clinically, this is typically pursued with high-intensity statin therapy, adding ezetimibe if the target isn’t reached, and considering a PCSK9 inhibitor if LDL-C remains above goal. While some cases may warrant even lower targets, <70 mg/dL is the commonly tested benchmark for very high‑risk ASCVD patients.

In patients with established ASCVD who are at very high risk, the goal is marked LDL-C lowering to reduce the chance of another event. Reaching an LDL-C level below 70 mg/dL provides a substantial reduction in recurrent cardiovascular events and is the standard target for secondary prevention in this group. Clinically, this is typically pursued with high-intensity statin therapy, adding ezetimibe if the target isn’t reached, and considering a PCSK9 inhibitor if LDL-C remains above goal. While some cases may warrant even lower targets, <70 mg/dL is the commonly tested benchmark for very high‑risk ASCVD patients.

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