A drug with a narrow therapeutic index requires which practice?

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Multiple Choice

A drug with a narrow therapeutic index requires which practice?

A drug with a narrow therapeutic index has a very small gap between the dose that produces benefit and the dose that causes toxicity. Because of this tight window, therapy must be approached with close monitoring. Clinicians use therapeutic drug monitoring when possible, check drug levels at appropriate times, and regularly assess organ function and signs of adverse effects. Dosing is adjusted based on measured concentrations and patient-specific factors such as kidney function, age, drug interactions, and weight, to keep levels within the safe and effective range. Constant dosing without monitoring isn’t inherently safe, and no monitoring or a wide safety margin would be inappropriate for such drugs.

A drug with a narrow therapeutic index has a very small gap between the dose that produces benefit and the dose that causes toxicity. Because of this tight window, therapy must be approached with close monitoring. Clinicians use therapeutic drug monitoring when possible, check drug levels at appropriate times, and regularly assess organ function and signs of adverse effects. Dosing is adjusted based on measured concentrations and patient-specific factors such as kidney function, age, drug interactions, and weight, to keep levels within the safe and effective range. Constant dosing without monitoring isn’t inherently safe, and no monitoring or a wide safety margin would be inappropriate for such drugs.

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